Histamine in brain development
نویسندگان
چکیده
منابع مشابه
Histamine in the brain
Brain histamine promotes wakefulness and orchestrates disparate behaviors and homeostatic functions. Recent evidence suggests that aberrant histamine signaling in the brain may also be a key factor in addictive behaviors and degenerative disease such as Parkinson’s diseases and multiple sclerosis. The intent of this research Topic is to provide an overview of the recent advances in the understa...
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BACKGROUND Histamine has been studied in both health and disease since the initial description a century ago. With its vasodilative effect, it was suggested early on to be involved in the pathophysiology of migraine. Over the past 25 years, much has been learned about histamine as a neurotransmitter in the central nervous system. The role of this neurotransmitter system in migraine has not been...
متن کاملThe role of histamine receptors in restraint stress-induced immunosuppression in the rat brain
Restraint-induced stress (RS) increases histamine concentration in the brain. There is no previous report regarding the role of histamine receptors in immunomodulatory effect of RS. In the present study the role of brain histamine receptors on reduction of humoral and cellular immune function induced by RS was evaluated. For this purpose male Wistar rats (200-250 g) were immunized with sheep re...
متن کاملBrain histamine and behavioral neuroscience
The human histaminergic system contains approximately 64.000 neurons located in a posterior region of the hypothalamus, the tuberomamillary nucleus. Projections of such a relatively small number of neurons are surprisingly widespread throughout the central nervous system. Histaminergic neurons are highly active during wakefulness and contribute to the physiology of arousal state, exploration, p...
متن کاملThe brain histamine system in vitro.
The electrophysiological properties of identified tuberomammillary histamine neurones were investigated in explant and slice preparations. The effects of histamine were studied on target neurones, mainly in the hippocampal slice. The results describe an important modulatory role of this diffusely projecting system.
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ژورنال
عنوان ژورنال: Journal of Neurochemistry
سال: 2012
ISSN: 0022-3042
DOI: 10.1111/j.1471-4159.2012.07863.x